Sunday, April 23, 2017

Scary Disease of the Week: Hemorrhagic Fevers

#3 Viral hemorraghic fevers. Ebola, Marburg, Machupo, RVF, lassa, and a dozen more emerging diseases. If you’re only in your 20’s, expect to see many more discovered in your lifetime. 

Ebola outbreaks. Zach Orecchio via wikimedia commons

These diseases get a lot of press, and they seem to be #1 on most people's list of scary disease, despite the infections being rare. I suspect it’s the image of bleeding profusely (which doesn’t often happen, and not exactly the way it’s often fictionally presented), particularly from the eyes, that hits our “fear button.” The horrible part of the disease to me is the pain. As the organs are attacked and become spongy, there is reportedly terrible abdominal pain associated with that. You have a fever, you’re weak and sick, the whites of your eyes may get a few red streaks, but the pain in your gut is what pins you to the bed.

The fatality rates on these diseases range from a low of less than 5% to a high of 70%--similar to the range of flu fatality rates. Zaire Ebola (EBOV) has one of the highest mortality rates. The R nought--how many people get infected by one sick person--isn’t that bad, actually, particularly not in the countries where my readers live. The infections spreading more than that in Africa is related to funeral practices there. Nearly half the people who have died of it are health care workers, and of the rest, half are the women family members who traditionally prepare bodies for burial. If scientists can convince people to forgo their typical burial practices with the dead bodies, the R nought for Ebola drops to near 1. Viral hemorrhagic fevers can also be passed sexually, after recovery, for three to five months.

To be weaponized, you’d want to increase that aspect of the disease, making is pass more easily from person to person. Currently, with Ebola, sneezing pigs can infect people easily but sneezing people cannot. It wouldn't take much time in a lab to change that fact. Everything else about any one of these diseases is bad enough, but were you a terrorist, you’d want it to move easily through the air so that one sick person infected many. If you could change the most deadly hemorrhagic fever virus so that it had measles’s skill at jumping from person to person, you’d have a terrible weapon indeed.  

Lassa virus


Stay tuned for scary diseases of the week #2 and #1. Can you guess what they are?

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